Eurofins Bioanalytical Services develops surrogate virus neutralising antibody detection assays against SARS-CoV-2

Posted by Kristy Galkowski on Feb 17, 2021 5:54:46 PM

Eurofins BioPharma News February 2021 FINAL WEB

The world is entering a new era of the COVID-19 pandemic in which there is an increasing call for reliable antibody testing. Conventional neutralising antibody serological testing requires the use of a live virus conducted in a Biosafety Level 3 (BSL-3) laboratory, which presents challenges for COVID-
19 development programmes. An alternative approach is the use of a surrogate virus test (sVNT) that removes this obstacle and is the first neutralising antibody serology test to
receive emergency use authorisation (EUA) from the FDA. This innovative assay detects the presence of neutralising/ blocking antibodies against the SARS-CoV-2 virus, that block the interaction between the receptor-binding domain (RBD) of the viral spike glycoprotein and the ACE2 cell surface receptor.

Current testing methods, such as PCR, determine whether someone is actively infected by confirming the presence of
viral material or IgG/IgM antibodies that detect (binding and blocking) induced immune response from exposure to the
virus. Being an ELISA methodology, the in-house, fully validated surrogate virus neutralisation test (sVNT) is
amenable to high-throughput testing, at a lower analytical cost, and requires no extended validation timelines for
Eurofins’ client base. It also removes the obstacle faced by many COVID-19 development programmes, by eliminating
the requirement for a Biosafety level 3 containment.

The advantage over historic antibody IgG/IgM tests is that this new gold standard assay tests for neutralising
antibodies (versus binding antibodies), by confirming neutralising function without the need for a secondary
antibody and is isotype and species independent. As the world strives to combat the COVID-19 pandemic,
Eurofins is committed to being part of global solution by expanding capacity to develop reagent kits and investments
in nonproprietary assays to offer for industry COVID-19 analytical Nab testing.

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Tags: Quality, Clinical Trial, Bioanalytical Testing, Pharmaceutical, Development, Immunology, SARS-CoV-2, neutralizing antibody testing

Join Us for the 2019 DIA Annual Meeting in San Diego, CA

Posted by Jesse Gehris on Jun 3, 2019 9:15:00 AM


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Eurofins Achieves 2019 CRO Leadership Award

Posted by Jesse Gehris on May 30, 2019 9:00:00 AM

For the 2019 CRO Leadership Awards, Life Science Leader magazine once again teamed up with Industry Standard Research (ISR) to determine the award recipients. More than 60 contract research organizations were assessed on over 20 performance metrics in ISR's annual CRO Quality Benchmarking survey. Eurofins is recognized as a recipient of these awards, exceeding customer expectations in every category.

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Tags: Quality, Results, Drug Development, Bioanalytical Testing, Development, BioPharma

Join Eurofins at the 2019 BIO Annual International Convention

Posted by Jesse Gehris on May 10, 2019 9:00:00 AM

Eurofins BioPharma Services will be attending the 2019 BIO International Convention in Philadelphia, June 3-6, to celebrate the globally important innovations in biotech that start with one: one meeting, one theory, one trial, one breakthrough. Join Eurofins BioPharma Services at Booth 2949 to consider how the largest wholly-owned network of BioPharma dedicated laboratories in the world can assist in your clinical trial research!

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Tags: Central Laboratory, Quality, Results, Clinical Trial, BioPharma

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