Expert Interview with Dr. Eric Bonner

Posted by Kristy Galkowski on Mar 28, 2019 2:19:14 PM


The immunogenecity of biologics is a significant concern, which can affect safety and efficacy. In this interview with Dr. Eric Bonner, we explore recent developments in immunogenecity, highlight key challenges when reviewing immunogenecity, and explore current regulations.

Immunogenecity is the ability of a therapeutic protein to stimulate an immune response, developing anti-drug antibodies to neutralize or bind the offending protein. It is an important assessment required for drug approvals that is measured and characterized. However, with the increase in biologics, how do scientists apply more sensitive and robust techniques and what challenges remain for assessing immunogenecity?


We aim to cover a range of developments, including:
  • Techniques utilized to investigate immunogenecity

  • Relationships between assay data and clinical outcome

  • Regulation and standardization

Click Here to Listen to Dr. Bonner's Interview


About Dr. Eric Bonner

eric-bonnerDr. Bonner serves as a scientific resource and technical advisor for both clients and internal teams in managing bioassays form development, to validation, to application. He received his Ph.D. in Biochemistry from the University of Illinois (Illinois, United States) in 2001, and has expertise in a wide variety of fields including protein chemistry, molecular biology, microbiology, and immunology. He has expertise in validating PK and biomarker assays, both single-plex and multi-plex, across a variety of analytical platforms. Dr. Bonner also has expertise in validation of anti-drug antibody assays, with a particular focus on the application of statistical methods for cut-point determination.



New call-to-action





Tags: Immune Cell Function, Drug Development, Development, BioPharma, Technology, Immunogenecity, Immunology

Global Leader in Biologics-focused Bioanalytical Solutions

Stay in the know and up-to-date on the latest Bioanalytical news, tips, and helpful links

  • Gain insight into the latest technology in the field
  • Focus on clinical research and laboratory services
  • Learn more about Biologics Done Right

Subscribe to Email Updates

Recent Posts